HIV Neurodegenerative Mechanisms Compared to Other Neurodegenerative Diseases – by Valquíria M. de Figueiredo, Tiago A. O. Silva

HIV Neurodegenerative Mechanisms Compared to Other Neurodegenerative Diseases – by Valquíria Merjan de Figueiredo, Tiago Andrade de Oliveira e Silva   Introduction This article describes HIV-1 factors and mechanisms involved in neurodegeneration and compares them with those of other neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Huntington’s disease. According to… Continue lendo…

HIV INFECTION AND DRUG ABUSE: IMPLICATIONS FOR NEUROPLASTICITY AND NEUROCOGNITIVE DISORDERS – Mônica Bento Bispo Patrícia de Barros Viegas

(Mônica Bento Bispo Patrícia de Barros Viegas) INTRODUCTION   Human immunodeficiency virus-1 (HIV-1) neuroinvasion occurs in about 80 % of infected individuals (Persidsky and Poluektova, 2006). In the early stage of infection, HIV enters the central nervous system (CNS) via infected monocytes, macrophages and T cells that cross the blood-brain… Continue lendo…