Dissociation, Delusion and the Splitting of the Self in The Trial by Franz Kafka: Phenomenology and Neurobiology of Schizophrenia- by Elisabete Castelon Konkiewitz and Edward Ziff

Abstract In this essay, we propose an association between Franz Kafka’s novel, The Trial, and phenomenological and neurobiological processes in schizophrenia. We begin by presenting a summary of the plot, pointing to some of its remarkable literary aspects. We next compare the mental processes of dissociation, disorientation and delusion as represented … Continue lendo…

HIV INFECTION AND DRUG ABUSE: IMPLICATIONS FOR NEUROPLASTICITY AND NEUROCOGNITIVE DISORDERS – Mônica Bento Bispo Patrícia de Barros Viegas

(Mônica Bento Bispo Patrícia de Barros Viegas) INTRODUCTION   Human immunodeficiency virus-1 (HIV-1) neuroinvasion occurs in about 80 % of infected individuals (Persidsky and Poluektova, 2006). In the early stage of infection, HIV enters the central nervous system (CNS) via infected monocytes, macrophages and T cells that cross the blood-brain … Continue lendo…

The role of dopaminergic dysfunction as an etiological factor in HIV-associated cognitive deficits and how it can be tested in animal models-by Francisco Catsarini, Jaume Aran and Marineide Aquino

  A major consequence of HIV infection is the development of cognitive deficits due to the effects of infection on the CNS. These deficits, usually referred to as HAND (HIV Associated Neurocognitive Disorders), are commonly classified in three categories, according to their severity: asymptomatic, mild and dementia. Although highly active … Continue lendo…